Download Biological Basis of Geriatric Oncology by Lodovico Balducci, Martine Extermann PDF

By Lodovico Balducci, Martine Extermann

Biological foundation of Geriatric Oncology highlights examine concerns which are particular to geriatric oncology within the box of carcinogenesis and melanoma prevention and therapy, in response to the biologic interactions of melanoma and age. It illustrates the good thing about the foundations of geriatrics within the administration of melanoma within the older individual.

This quantity presents a body of reference for practicioners of any specialties considering the administration of older sufferers and for oncologists all for the administration of melanoma of older participants. it's a resource for simple and scientific scientists exploring the interactions and rising details of melanoma and aging.

Show description

Read Online or Download Biological Basis of Geriatric Oncology PDF

Best geriatrics books

Practical Management of Depression in Older People (Hodder Arnold Publication)

The textual content examines the several remedies for melancholy within the aged. It exhibits how the multi-disciplinary workforce may possibly impact the effectiveness of such remedies and discusses the sensible implications.

The handholder's handbook: a guide to caregivers of people with Alzheimer's or other dementias

 In a countrywide survey, 19 million americans acknowledged they've got a friend with Alzheimer's, and 37 million stated they knew somebody who had it. but if Rosette Teitel came upon herself within the function of caregiver to her in poor health husband, she may well locate no books that replied her useful wishes: How do you provide a 170-pound guy a bath?

Führungskompetenz für Leitende Ärzte: Motivation, Teamführung, Konfliktmanagement im Krankenhaus

Setzen Sie Impulse! Insbesondere von Leitenden Ärzten werden neben den medizinischen zunehmend auch Führungs- Kompetenzen erwartet. Diese Kompetenzen sind nachweislich karrierefördernd. Konkrete Beispiele aus dem ärztlichen Führungsalltag in der KlinikHandfeste Praxisempfehlungen – wissenschaftlich abgesichert/belegt(Beispiele aus dem Klinikalltag in Kombination mit dem dazugehörigen psychologischen Hintergrund)Lösungsstrategien, um souverän und erfolgreich zu agierenInterviews mit anerkannten Führungskräften aus dem Kliniksektor und aus meinungsbildenden Verbänden: Vorstände, Geschäftsführer, ärztliche DirektorenFührungstools für Leitende Ärzte: Checklisten, Kopiervorlagen für Mitarbeitergespräche, exams für Situationstransparenz und –klärung, assessments für den Abgleich von Selbst- und Fremdbild …Führungspersönlichkeiten in der Medizin gelingt es, ihre ärztlichen Mitarbeiter zu motivieren.

Dementia in Clinical Practice: A Neurological Perspective: Pragmatic Studies in the Cognitive Function Clinic

This concise, pragmatic, pocket-sized publication addresses neurological contributions to the analysis and administration of dementia via a longitudinal exam of the paintings undertaken in a devoted neurological dementia health facility. It covers using cognitive and non-cognitive screening tools and their diagnostic software and using different diagnostic investigations: neuroimaging, neurophysiology and neuropathology.

Additional info for Biological Basis of Geriatric Oncology

Example text

Thus, stimulation of uptake of glucose in tissues by biguanides inhibits lipogenesis and activates oxidation of FFA 149. It was shown also that in vivo biguanides inhibits an appetite 150,151 and serum levels of leptin and IGF-1 152. It was suggested that biguanides regulate energy balance of the organism at the fat tissue level 153. In general, results of bioguanides effects seem very similar to those of calorie restriction. BIOLOGICAL INTERACTIONS 41 42 V. ANISIMOV 8. CONCLUSION The incidence of cancer increases with age in humans and in laboratory animals alike, but patterns of age-related distribution of tumors is different for different tissues and different tumors.

BIOLOGICAL INTERACTIONS 21 Figure 2. Integral scheme of carcinogenesis a minimum of one intermediate stage). Secondly, passage from one stage to another is a stochastic event, the rate of which depends on the dose of a carcinogen that affects the cell. Finally, all cells at any stage of carcinogenesis may enter the next stage independently of each other. According to this model, the tumor develops only if at least one cell goes through all the necessary stages, and the clonal growth of this cell causes clinical cancer, as a critical volume of neoplastic cells accumulates.

Two main pathways the extracellular-signal related kinase (ERK)/mitogen-activated protein kinase (MAPK) pathway and the phosphatidylinositol 3-kinase (PI3K)-Akt pathway – were downregulated in mice. The extension of longevity was observed in fat-specific insulin receptor knockout (FIRKO) mice 114,115. These animals have reduced fat mass and were protected against age-related obesity and its subsequent metabolic abnormalities including deterioration in glucose tolerance, although their food intake was normal.

Download PDF sample

Rated 4.95 of 5 – based on 22 votes

About admin