
By Shabir H. Lone, Khursheed Ahmad Bhat, Mohammad Akbar Khuroo
This booklet reports the chemical and organic houses of Artemisia amygdalina Decne, a seriously endangered and endemic plant species within the the high-altitude Kashmir Himalayas, which has a excessive pharmacological strength. It describes the bioactivity-guided isolation of its chemical substances, their characterization utilizing spectroscopic equipment and the improvement of an easy and trustworthy RP-HPLC procedure for the simultaneous quantification of the remoted elements. The authors speak about the capability pharmacological actions of A. amygdalina, resembling antioxidant, cytotoxic, anti inflammatory, immuno-modulatory and antidiabetic results, and pave the way in which for destiny research.
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As compared to normal group, the glucose levels of experimental rats treated with extracts and glibenclamide showed a steep reduction. ) showed more significant antihyperglycemic activity than other extracts and glibenclamide treated rats. 12).
6). (2013). Carrageenan-induced paw edema has been carried out to study the anti-inflammatory potential of A. 6 Agarose gel electrophoresis for DNA damage inhibition assay by A. amygdalina methanolic extracts. 2 Anti-inflammatory and Immunomodulatory Potential … 45 Decne. To study the immunomodulatory potential of A. amygdalina Decne, SRBC-specific haemagglutination titer and DTH assays have been carried out in Balb/C mice. 1962) has been utilized to assess the acute anti-inflammatory potential of the A.
06 µg mL−1), respectively, against DPPH radical. 1). 04 µg mL−1), respectively, against superoxide radicals. 1). 1 IC50 values of petroleum ether (P), ethyl acetate (E), methanol (M), and aqueous (W) extracts of in vitro grown (T) and greenhouse raised plants (G) of A. 96 µg mL−1), respectively, against hydroxyl radicals generated by Fentons reaction. 1). 46 µg mL−1), respectively, against lipid peroxyl radicals generated by oxidation of linoleic acid. 1). 93 µg mL−1), respectively, against TBA reactive species.