By Clay Cockerell, Martin C. Mihm Jr., Brian J. Hall, Cary Chisholm, Chad Jessup, Margaret Merola
Dermatopathology is a really good department of pathology during which there was nice development as new concepts became on hand to judge the pathology of the surface. the various advances in our wisdom and knowing of the surface and the ailments that impact it were made by way of individuals with event of either diagnostic pathology and scientific dermatology. With major numbers of huge textbooks on hand, there's a have to supply useful medical info and concise standards for pathologic prognosis for pathologists and dermatologists trying to find up to date diagnostic and administration options.
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Hyphae are refractile structures on H&E, but they may be highlighted with a PAS or GMS stain. Majocchi’s granuloma shows hyphae tracking down hair shafts/follicular infundibula with accompanying perifollicular chronic inflammation. Differential Diagnosis: Candidiasis, atopic dermatitis, contact dermatitis, impetigo, seborrheic dermatitis, folliculitis, PR. Clinical: Urticarial papules that may vesiculate and are often excoriated. Clinical features can vary greatly depending on the type of arthropod.
Differential Diagnosis: PLEVA, lymphomatoid papulosis, arthropod assault, drug eruption, erythema multiforme, mycosis fungoides. b c Fig. 9 (a) Exocytosis and vacuolar interface change are seen. There are a few extravasated red blood cells, but they are not prominent (hematoxylin and eosin, 20×). (b) There is a relatively light lichenoid lymphocytic infiltrate (hematoxylin and eosin, 4×). (c) The sparse lichenoid infiltrate does extend up to the epidermis with intraepidermal lymphocytes being common.
2003;25(6):451–62. 3 Psoriasiform Dermatoses Psoriasis Clinical: Psoriasis is a disease with complicated genetics and pathogenesis. There are multiple inciting factors, and the different treatments provide variable efficacy. There are numerous variants, which have some similar histopathological findings. In general, psoriasis is a chronic, relapsing disorder. Patients are affected by multiple well-circumscribed papules or plaques with overlying silver scale. When the scale is removed, the lesions typically bleed – the so-called Auspitz sign.