By A.J. Larner
This ebook explains the major steps in making plans and executing diagnostic try accuracy experiences in dementia, with transparent reasons of problems and pitfalls and with jargon sincerely defined. The emphasis is on pragmatic diagnostic try out accuracy reports which might be built-in into daily medical perform. The e-book relies at the author’s adventure over greater than 10 years, which has ended in the booklet of many diagnostic try out accuracy studies.
The textual content is established as for a learn book on a diagnostic try accuracy research (Introduction, tools, effects, Discussion), with a last bankruptcy on destiny customers. all the chapters is dedicated to a pragmatic and dependent assessment of every of those steps in acting and writing up this type of study.
Diagnostic try out Accuracy reports in Dementia: a practical Approach is aimed toward any clinician with an curiosity in dementia issues: previous age psychiatrists, geriatricians, neurologists, neuropsychologists and first care physicians, in addition to different professions allied to medication. The publication is additionally of curiosity to any clinician/researcher with an curiosity in diagnostic attempt accuracy studies.
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Extra resources for Diagnostic Test Accuracy Studies in Dementia: A Pragmatic Approach
2000). Of course these study participants are not necessarily those amongst whom it is clinically sensible to suspect the target disorder (phase II question: Sackett and Haynes 2002:24). By exaggerating the contrast between patients and controls (ideal or extreme contrast settings), test specificity will be inflated (Sect. 2). Another rider is that a control group comprising individuals with “normal ageing” may harbour individuals with subclinical disease, a problem generic to any study of age-related signs (Larner 2012b).
Larner AJ. Can IQCODE differentiate Alzheimer’s disease and frontotemporal dementia? Age Ageing. 2010b;39:392–4. Larner AJ. Audit of practice versus guidelines: neuro-imaging in a dementia clinic. Morecambe Bay Med J. 2011;6:110–2. Larner AJ. Pragmatic diagnostic accuracy studies. com/content/345/bmj. tab=responses, 28 Aug 2012a. Larner AJ. Screening utility of the Montreal Cognitive Assessment (MoCA): in place of - or as well as - the MMSE? Int Psychogeriatr. 2012b;24:391–6. Larner AJ. Mini-Mental Parkinson (MMP) as a dementia screening test: comparison with the Mini-Mental State Examination (MMSE).
The evidence base of clinical diagnosis. London: BMJ Books; 2002a. p. 19–38. Sackett DL, Haynes RB. The architecture of diagnostic research. BMJ. 2002b;324:539–41. Schulz KF, Chalmers I, Hayes RJ, Altman DG. Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA. 1995;273:408–12. Scottish Intercollegiate Guidelines Network. Methodology checklist 5: studies of diagnostic accuracy. In: A guideline developer’s handbook.