By Manfred Oehmichen
Incorporating the latest literature and cutting-edge tools, this useful paintings and atlas covers the whole area of neuropathology for forensic pathologists in addition to for experts in linked fields. Its concise, direct type presents the reader with succinct and easy-to-find solutions to forensic, pathological, pathophysiological, biomechanical, and molecular biology difficulties. also, the authors hide a number of easy and useful difficulties that can stimulate additional research.
Each bankruptcy comprises an summary of the literature in addition to detailed references, and contours a wealth of figures, graphs, and tables.
The current quantity bargains with particular features of neuropathology, and is especially applicable for all these and eager about the sector of forensic pathology, forensic sciences, scientific pathology, neurology, neurosurgery, legislation, and criminology. unique emphasis is put on services in regards to the field's relevance for daily perform and likewise on updated info in simple research.
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Additional info for Forensic Neuropathology and Associated Neurology
In this case, the event must be the “main and essential” cause of the effects. To define one cause as main and essential presupposes that its action must be so prominent that without its effects the lesion ought not to have arisen at all nor else with the same speed of development nor to the same degree. There can be a wide-ranging debate as to whether a particular event produced or contributed to a particular result. Like all legal concepts, the term “causation” is applied with an aim to guiding activity and redressing grievance by representing a consequence of factual activity in terms of a doctrine supporting the law‘s purposes.
Protoplasmic astrocytes (gray matter astrocytes − Fig. 4c). Protoplasmic astrocytes have ramified processes of variable caliber. Most astrocytes residing in normal gray matter are GFAP negative, and this is the basis for determining reactive gliosis. GFAP-positive astrocytes in the gray matter are small and possess many short processes radiating from the cell body, which is usually poorly marked by GFAP immunoreactivity. 3. Radial astrocytes (white matter astrocytes). These cells, disposed in a plane perpendicular to the axis of the ventricles, are of particular importance during CNS embryology (Rakic 1995; Parnavelas and Nadarajahn 2001).
This cell type exhibits a homogeneous cytoplasm and a slightly enlarged nucleus with angular projections from which the processes arise. The nucleus is lateralized to one side of the cell body and may be irregularly rounded. , growth factors and neuropeptides) via extracellular signal-regulated kinase and mitogenactivated protein kinase (Mandell 2001). In certain respects, reactive astrocytes resemble neurons undergoing central chromatolysis, which is a basic reaction to axonal transection (Bignami and Dahl 1995 − see below, p.