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Cohen explores Houghton Mifflin, Boston, uterus is presumably pro- prisingly inefficient in its reproductive efforts. They may also provide therapies targeted to the many strands of miscarriage 2005. 288 pp. $24. ISBN 0- grammed to reject. Unfortunately we are in the help people for whom full-term pregnancy just research from the mid 20th cen- 618-27724-2. dark about both the mecha- does not come easily. Meanwhile, Cohen’s tury to the present; he talked to couples with tragic and, in some cases, nisms that underlie the loss of normal book provides a valuable resource for couples extraordinary histories of repeated pregnancy embryos and the extent to which immune seeking help in deciding a course of action in failure; and he got to know doctors who do recognition contributes to the “normal” the face of difficulties with starting a family.

Although this could be a reasonable approach for data with a Gaussian probability distribution, this is not the case for Letters to the Editor \ Letters (~300 words) discuss material published in Science in the previous 6 months or issues of general interest. , NW, Washington, DC 20005, USA). Letters are not acknowledged upon receipt, nor are authors generally consulted before publication. Whether published in full or in part, letters are subject to editing for clarity and space. org SCIENCE 14C dates, where calibration nearly always gives rise to highly multimodal distributions.

The asthma responses. Knockout of type 1 GSNOR chronic inflammation of the asthmatic lung NOS (the neuronal variant) produced (NH3) + GSSG results from an allergic reaction marked by a mild (~threefold) decrease in airway elevated immunoglobulin E, mast cells and Production and fate of S-nitrosoglutathione. NO, hyperresponsiveness, suggesting that eosinophils, and cytokines such as inter- produced by an NO synthase, reacts with glutathione to this isoform was responsible for leukin-5 and interleukin-13.

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